〜を皮切りに(して)
starting with, beginning with (and then spreading)
Noun + を皮切りに(して) / を皮切りとして
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を皮切りに names the first in a series of events that then spread or continue: 東京公演を皮切りに、全国ツアーが始まる, "the national tour kicks off with a show in Tokyo".
The second half is a series or expansion: a tour, a run of complaints, new branches opening, a wave of people speaking out. It's common in news, business and entertainment.
Compare をはじめ (N3), "including, starting with", which lists representative members of a group that already exists. を皮切りに is about time: this was the first, and more followed.
皮切り originally meant the first moxibustion treatment on the skin, the first "cut".
Examples
東京公演を皮切りに、全国ツアーが始まる。
The national tour kicks off with a show in Tokyo.
彼の発言を皮切りに、次々と反対意見が出た。
Starting with his remark, one objection followed another.
大阪店を皮切りに、海外にも出店した。
Beginning with the Osaka shop, they opened stores abroad as well.
今日の会議を皮切りに、話し合いを重ねていく。
Starting with today's meeting, we'll hold a series of discussions.
一人の告白を皮切りに、多くの被害者が声を上げた。
One person's confession was the first of many victims speaking out.