〜に至っては
as for (the most extreme case)
Noun + に至っては
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に至っては singles out the most extreme example in a series, usually of something bad: 英語も苦手だが、数学に至ってはゼロ点だった, "I'm bad at English, but as for maths, I got zero".
The sentence usually starts by describing a general situation (everyone is against it, prices are rising), then に至っては introduces the worst case (my father won't even speak to me, vegetables cost double).
It's formal and written. 至る means "to reach", so it's literally "when it reaches X". Compare に至って (N1), "only when it reached (that point)", and に至るまで, "right down to".
Don't confuse it with にとっては (N3), "for, from the point of view of".
Examples
英語も苦手だが、数学に至ってはゼロ点だった。
I'm bad at English, but as for maths, I got zero.
家族は皆反対で、父に至っては口もきいてくれない。
My whole family is against it, and my father won't even speak to me.
最近は物価が上がり、野菜に至っては去年の二倍だ。
Prices are rising, and vegetables are twice what they were last year.
クラスの半分が遅刻し、田中君に至っては来なかった。
Half the class was late, and Tanaka didn't show up at all.
どの店も高いが、この店に至ってはコーヒー一杯が二千円だ。
Every shop is expensive, but this one charges two thousand yen for a coffee.